About NORI Protocol. NORI has researched and developed a unique approach to cancer therapy that is very simple, effective, low-cost, nontoxic and can be implemented at home by the cancer patient. It is based on targeting common metabolic abnormalities present in nearly all types of cancer cells. A methionine restricted diet combined with a nontoxic chemotherapeutic cocktail is a unique and powerful approach to treating and managing malignancies.
An important feature of the NORI protocol is the synergy created between the methionine restricted diet and high dose selenium. Methionine restriction sensitizes cancer cells to sodium selenite by lowering glutathione which increases oxidative stress.
The NORI approach is to leverage diet for maximum benefit while using a straightforward and highly targeted method for selectively killing cancer cells.
Methionine Restricted Diet
Nutrition is a powerful tool in controlling tumor growth as well as making cancer cells much more susceptible to treatment. The trick is in supporting normal healthy cells while depriving cancer cells of essential nutrients. Cancer cells are highly dependent on several different amino acids for growth and cell division. Cancer cells are universally dependent on methionine. It is both practical and effective to limit the dietary intake of methionine as a means to starve cancer cells of this essential nutrient. Normal cells are unharmed by short term limitation of methionine. Methionine restriction is very powerful and may be sufficient as a standalone therapy for many early stage cancers. Click here to read an article on dietary methionine restriction published in 2001 by Dr Epner.
NORI does not encourage or support the use of nutritional supplements, herbs and juicing during cancer treatment. It is believed that these elements only help cancer cells grow and survive. Anti-cancer compounds are only helpful if they are adequately absorbed, are present in the bloodstream at a sufficient concentration and time interval.
Methionine restriction is individualized for each patient according to weight, nutritional status, disease progression and past dietary preferences. A methionine restricted diet may be continuous or cycled on and off depending on individual circumstances. Methionine restriction involves the elimination of many foods and a focus on mostly fruits. The natural sugars in fruits will not feed cancer cells or cause tumors to grow. It is a common misconception that fruit equals sugar and that fruits raise blood sugar. Fruit can be a problem if there is a high fat intake (greater than 10% of total caloric intake) which will cause insulin resistance.
High Dose Selenium
Selenium is an essential trace element found in foods and nutritional supplements. Studies have shown that selenium not only can prevent cancer but can also treat it. Click here to read one of the best papers on treating cancer with selenium by Eric Olm, PhD.
Sodium selenite is the most effective form of selenium for therapeutic use. Cancer cells are triggered to self destruct (apoptosis) when exposed to sodium selenite at low concentrations. Normal healthy cells are unharmed unlike treatment with conventional chemotherapy. Sodium selenite can be administered intravenously or by the use of a specially formulated sublingual tablet.
Sodium selenite is combined with two other natural compounds to boost the effect so that very safe and low doses can be used very effectively. The mechanism of action is pro-oxidative through a simple chemical reaction that generates excess reactive oxygen species within the mitochondria which releases a cascade of signals triggering apoptosis.
NORI does not sell therapeutic level sodium selenite supplements and IV solutions to individuals. Sodium selenite is available to patients who are receiving care from an affiliated physician or who are participating in the NORI nutritional support program. The types and dosages of selenium available in health food stores and online will not have therapeutic value. Selenized yeast at 200 mcg per day is the best form for cancer prevention.
Genipin is a compound present in gardenia fruit extract (Zhi Zi) that has been found to inhibit a mitochondrial protein called UCP2. Genipin has been shown to trigger apoptosis through the generation of excess reactive oxygen species (ROS) by increasing the level of ATP generated by mitochondria. UCP2 maintains the cancer cell at a low level of oxidative stress by keeping the level of mitochondrial oxidative phosphorylation minimized. Gardenia fruit extract (Zhi Zi) has been used in traditional Chinese medicine for thousands of years. Current scientific studies are demonstrating potent and selective anti-tumor activity.
Vitamin E Succinate
The semi-synthetic form of vitamin E, vitamin E succinate (VES) has been extensively studied as a cancer preventative and chemotherapeutic agent. NORI incorporates VES within a powerful cocktail designed to induce apoptosis through the generation of excess oxidative stress. VES has no antioxidant activity and is synergistic with the pro-oxidant effects of sodium selenite. VES reacts directly with mitochondrial complex II generating ROS and has been shown to trigger apoptosis in over 90% of cancer cell types. VES is completely nontoxic to normal cells. NORI uses a transdermal VES formulation in addition to oral administration to ensure optimal therapeutic blood plasma concentration.
A Simple but Powerful Approach
The NORI protocol is very simple to implement but may be one of the most powerful alternative cancer treatments ever developed. By optimally timing and synchronizing cycles the methionine restricted diet with the administration of the cocktail, cancer cells loose all defenses and nutrients necessary for growth and division. The NORI protocol directly targets the cancer cell’s mitochondria which is exactly the root of the problem from the onset of the disease process.
For more information about NORI Protocol, call 1-800-634-3804 or email us info@NutritionalOncology.net.